Predicting synonymous codon usage and optimizing the heterologous gene for expression in E. coli

Of the 20 common amino acids, 18 are encoded by multiple synonymous codons. These synonymous codons are not redundant; in fact, all of codons contribute substantially to protein expression, structure and function. In this study, the codon usage pattern of genes in the E. coli was learned from the se...

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Detalles Bibliográficos
Autores principales: Tian, Jian, Yan, Yaru, Yue, Qingxia, Liu, Xiaoqing, Chu, Xiaoyu, Wu, Ningfeng, Fan, Yunliu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577221/
https://www.ncbi.nlm.nih.gov/pubmed/28855614
http://dx.doi.org/10.1038/s41598-017-10546-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577221/
https://www.ncbi.nlm.nih.gov/pubmed/28855614
http://dx.doi.org/10.1038/s41598-017-10546-0

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