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Predicting synonymous codon usage and optimizing the heterologous gene for expression in E. coli
Of the 20 common amino acids, 18 are encoded by multiple synonymous codons. These synonymous codons are not redundant; in fact, all of codons contribute substantially to protein expression, structure and function. In this study, the codon usage pattern of genes in the E. coli was learned from the se...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577221/ https://www.ncbi.nlm.nih.gov/pubmed/28855614 http://dx.doi.org/10.1038/s41598-017-10546-0 |