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Transforming Growth Factor Beta is regulated by a Glucocorticoid-Dependent Mechanism in Denervation Mouse Bone

Bone growth and remodeling is inhibited by denervation in adults and children, resulting in alterations of linear growth and bone mass and increased risk for osteoporosis and pathologic fractures. Transforming growth factor beta (TGF-β) isoforms are a key group of growth factors that enhance bone fo...

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Detalles Bibliográficos
Autores principales: Li, Ye, Jie, Ligang, Tian, Austin Y., Zhong, Shenrong, Tian, Mason Y., Zhong, Yixiu, Wang, Yining, Li, Hongwei, Li, Jinlong, Sun, Xiaoyan, Du, Hongyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577242/
https://www.ncbi.nlm.nih.gov/pubmed/28855536
http://dx.doi.org/10.1038/s41598-017-09793-y