HuR-targeted small molecule inhibitor exhibits cytotoxicity towards human lung cancer cells

Human antigen (Hu) R is an RNA-binding protein whose overexpression in human cancer correlates with aggressive disease, drug resistance, and poor prognosis. HuR inhibition has profound anticancer activity. Pharmacologic inhibitors can overcome the limitations of genetic inhibition. In this study, we...

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Detalles Bibliográficos
Autores principales: Muralidharan, Ranganayaki, Mehta, Meghna, Ahmed, Rebaz, Roy, Sudeshna, Xu, Liang, Aubé, Jeffrey, Chen, Allshine, Zhao, Yan Daniel, Herman, Terence, Ramesh, Rajagopal, Munshi, Anupama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577245/
https://www.ncbi.nlm.nih.gov/pubmed/28855578
http://dx.doi.org/10.1038/s41598-017-07787-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577245/
https://www.ncbi.nlm.nih.gov/pubmed/28855578
http://dx.doi.org/10.1038/s41598-017-07787-4

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