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Massive transcriptome sequencing of human spinal cord tissues provides new insights into motor neuron degeneration in ALS

ALS is a devastating and debilitating human disease characterized by the progressive death of upper and lower motor neurons. Although much effort has been made to elucidate molecular determinants underlying the onset and progression of the disorder, the causes of ALS remain largely unknown. In the p...

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Detalles Bibliográficos
Autores principales: D’Erchia, Anna Maria, Gallo, Angela, Manzari, Caterina, Raho, Susanna, Horner, David S., Chiara, Matteo, Valletti, Alessio, Aiello, Italia, Mastropasqua, Francesca, Ciaccia, Loredana, Locatelli, Franco, Pisani, Francesco, Nicchia, Grazia Paola, Svelto, Maria, Pesole, Graziano, Picardi, Ernesto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577269/
https://www.ncbi.nlm.nih.gov/pubmed/28855684
http://dx.doi.org/10.1038/s41598-017-10488-7