Intranasally administered in situ gelling nanocomposite system of dimenhydrinate: preparation, characterization and pharmacodynamic applicability in chemotherapy induced emesis model

The aim of the current manuscript was to test the applicability of a nanocomposite system of penetration enhancer vesicles (PEVs) within polymeric in situ forming gel network composed of poloxamer and hyaluronic acid for the intranasal delivery of the antiemetic dimenhydrinate (DMH). PEVs were prepa...

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Detalles Bibliográficos
Autores principales: Barakat, Sara S., Nasr, Maha, Ahmed, Rania F., Badawy, Sabry S., Mansour, Samar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577313/
https://www.ncbi.nlm.nih.gov/pubmed/28855590
http://dx.doi.org/10.1038/s41598-017-10032-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577313/
https://www.ncbi.nlm.nih.gov/pubmed/28855590
http://dx.doi.org/10.1038/s41598-017-10032-7

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