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PPARα activation protects against cholestatic liver injury

Intrahepatic cholestasis induced by drug toxicity, bile salt export pump (BSEP) deficiency, or pregnancy frequently causes cholestatic liver damage, which ultimately may lead to liver fibrosis and cirrhosis. Here, the preventive and therapeutic effects of peroxisome proliferator-activated receptor α...

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Detalles Bibliográficos
Autores principales: Zhao, Qi, Yang, Rui, Wang, Jing, Hu, Dan-Dan, Li, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577315/
https://www.ncbi.nlm.nih.gov/pubmed/28855630
http://dx.doi.org/10.1038/s41598-017-10524-6