Cargando…
Determination of the physiological and pathological roles of E2F3 in adult tissues
While genetically engineered mice have made an enormous contribution towards the elucidation of human disease, it has hitherto not been possible to tune up or down the level of expression of any endogenous gene. Here we describe compound genetically modified mice in which expression of the endogenou...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577339/ https://www.ncbi.nlm.nih.gov/pubmed/28855541 http://dx.doi.org/10.1038/s41598-017-09494-6 |