Determination of the physiological and pathological roles of E2F3 in adult tissues

While genetically engineered mice have made an enormous contribution towards the elucidation of human disease, it has hitherto not been possible to tune up or down the level of expression of any endogenous gene. Here we describe compound genetically modified mice in which expression of the endogenou...

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Detalles Bibliográficos
Autores principales: Gamper, Ivonne, Burkhart, Deborah L., Bywater, Megan J., Garcia, Daniel, Wilson, Catherine H., Kreuzaler, Peter A., Arends, Mark J., Zheng, Yao-Wu, Perfetto, Alessandra, Littlewood, Trevor D., Evan, Gerard I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577339/
https://www.ncbi.nlm.nih.gov/pubmed/28855541
http://dx.doi.org/10.1038/s41598-017-09494-6

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