Genetic Analysis in UK Biobank Links Insulin Resistance and Transendothelial Migration Pathways to Coronary Artery Disease

UK Biobank is among the world’s largest repositories for phenotypic and genotypic information in individuals of European ancestry(1). We performed a genome-wide association study in UK Biobank testing ~9 million DNA sequence variants for association with coronary artery disease (4,831 cases; 115,455...

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Detalles Bibliográficos
Autores principales: Klarin, Derek, Zhu, Qiuyu Martin, Emdin, Connor A., Chaffin, Mark, Horner, Steven, McMillan, Brian J., Leed, Alison, Weale, Michael E., Spencer, Chris C. A., Aguet, François, Segrè, Ayellet V., Ardlie, Kristin G., Khera, Amit V., Kaushik, Virendar K., Natarajan, Pradeep, Consortium, CARDIoGRAMplusC4D, Kathiresan, Sekar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577383/
https://www.ncbi.nlm.nih.gov/pubmed/28714974
http://dx.doi.org/10.1038/ng.3914

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577383/
https://www.ncbi.nlm.nih.gov/pubmed/28714974
http://dx.doi.org/10.1038/ng.3914

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