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Genetic Analysis in UK Biobank Links Insulin Resistance and Transendothelial Migration Pathways to Coronary Artery Disease
UK Biobank is among the world’s largest repositories for phenotypic and genotypic information in individuals of European ancestry(1). We performed a genome-wide association study in UK Biobank testing ~9 million DNA sequence variants for association with coronary artery disease (4,831 cases; 115,455...
Autores principales: | Klarin, Derek, Zhu, Qiuyu Martin, Emdin, Connor A., Chaffin, Mark, Horner, Steven, McMillan, Brian J., Leed, Alison, Weale, Michael E., Spencer, Chris C. A., Aguet, François, Segrè, Ayellet V., Ardlie, Kristin G., Khera, Amit V., Kaushik, Virendar K., Natarajan, Pradeep, Consortium, CARDIoGRAMplusC4D, Kathiresan, Sekar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577383/ https://www.ncbi.nlm.nih.gov/pubmed/28714974 http://dx.doi.org/10.1038/ng.3914 |
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