Misidentified Human Gene Functions with Mouse Models: The Case of the Retinoblastoma Gene Family in Senescence()()()

Although mice models rank among the most widely used tools for understanding human genetics, biology, and diseases, differences between orthologous genes among species as close as mammals are possible, particularly in orthologous gene pairs in which one or more paralogous (i.e., duplicated) genes ap...

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Detalles Bibliográficos
Autores principales: Alessio, Nicola, Capasso, Stefania, Ferone, Angela, Di Bernardo, Giovanni, Cipollaro, Marilena, Casale, Fiorina, Peluso, Gianfranco, Giordano, Antonio, Galderisi, Umberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2017
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577395/
https://www.ncbi.nlm.nih.gov/pubmed/28865301
http://dx.doi.org/10.1016/j.neo.2017.06.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577395/
https://www.ncbi.nlm.nih.gov/pubmed/28865301
http://dx.doi.org/10.1016/j.neo.2017.06.005

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