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Misidentified Human Gene Functions with Mouse Models: The Case of the Retinoblastoma Gene Family in Senescence()()()
Although mice models rank among the most widely used tools for understanding human genetics, biology, and diseases, differences between orthologous genes among species as close as mammals are possible, particularly in orthologous gene pairs in which one or more paralogous (i.e., duplicated) genes ap...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Neoplasia Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577395/ https://www.ncbi.nlm.nih.gov/pubmed/28865301 http://dx.doi.org/10.1016/j.neo.2017.06.005 |