The Imipridone ONC201 Induces Apoptosis and Overcomes Chemotherapy Resistance by Up-Regulation of Bim in Multiple Myeloma

In multiple myeloma, despite recent improvements offered by new therapies, disease relapse and drug resistance still occur in the majority of patients. Therefore, there is an urgent need for new drugs that can overcome drug resistance and prolong patient survival after failure of standard therapies....

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Detalles Bibliográficos
Autores principales: Tu, Yong-sheng, He, Jin, Liu, Huan, Lee, Hans C., Wang, Hua, Ishizawa, Jo, Allen, Joshua E., Andreeff, Michael, Orlowski, Robert Z., Davis, Richard E., Yang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2017
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577403/
https://www.ncbi.nlm.nih.gov/pubmed/28863346
http://dx.doi.org/10.1016/j.neo.2017.07.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577403/
https://www.ncbi.nlm.nih.gov/pubmed/28863346
http://dx.doi.org/10.1016/j.neo.2017.07.009

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