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Chronic exposure to dopamine agonists affects the integrity of striatal D(2) receptors in Parkinson's patients

We aimed to investigate the integrity and clinical relevance of striatal dopamine receptor type-2 (D(2)R) availability in Parkinson's disease (PD) patients. We studied 68 PD patients, spanning from early to advanced disease stages, and 12 healthy controls. All participants received one [(11)C]r...

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Detalles Bibliográficos
Autores principales: Politis, Marios, Wilson, Heather, Wu, Kit, Brooks, David J., Piccini, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577411/
https://www.ncbi.nlm.nih.gov/pubmed/28879087
http://dx.doi.org/10.1016/j.nicl.2017.08.013