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ZC4H2 stabilizes Smads to enhance BMP signalling, which is involved in neural development in Xenopus

Bone morphogenetic proteins (BMPs) play vital roles in regulating stem cell maintenance, differentiation and embryonic development. Intracellularly, BMP signalling is mediated by Smad proteins, which are regulated post-transcriptionally through reversible phosphorylation and ubiquitination. ZC4H2 is...

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Detalles Bibliográficos
Autores principales: Ma, Pengcheng, Ren, Biyu, Yang, Xiangcai, Sun, Bin, Liu, Xiaoliang, Kong, Qinghua, Li, Chaocui, Mao, Bingyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577449/
https://www.ncbi.nlm.nih.gov/pubmed/28814648
http://dx.doi.org/10.1098/rsob.170122