The role of ubiquitin-dependent segregase p97 (VCP or Cdc48) in chromatin dynamics after DNA double strand breaks

DNA double strand breaks (DSBs) are the most cytotoxic DNA lesions and, if not repaired, lead to chromosomal rearrangement, genomic instability and cell death. Cells have evolved a complex network of DNA repair and signalling molecules which promptly detect and repair DSBs, commonly known as the DNA...

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Detalles Bibliográficos
Autores principales: Torrecilla, Ignacio, Oehler, Judith, Ramadan, Kristijan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577460/
https://www.ncbi.nlm.nih.gov/pubmed/28847819
http://dx.doi.org/10.1098/rstb.2016.0282

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577460/
https://www.ncbi.nlm.nih.gov/pubmed/28847819
http://dx.doi.org/10.1098/rstb.2016.0282

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