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DNA repair goes hip-hop: SMARCA and CHD chromatin remodellers join the break dance
Proper signalling and repair of DNA double-strand breaks (DSB) is critical to prevent genome instability and diseases such as cancer. The packaging of DNA into chromatin, however, has evolved as a mere obstacle to these DSB responses. Posttranslational modifications and ATP-dependent chromatin remod...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Royal Society
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577463/ https://www.ncbi.nlm.nih.gov/pubmed/28847822 http://dx.doi.org/10.1098/rstb.2016.0285 |