LiTMP Trans‐Metal‐Trapping of Fluorinated Aromatic Molecules: A Comparative Study of Aluminum and Gallium Carbanion Traps

Fluoroaromatic scaffolds pose a challenge to lithiation due to low stability of lithiated intermediates. Here we apply trans‐metal‐trapping (TMT) to a series of key fluorinated aromatics. In TMT, LiTMP performs the metalation, while an organometallic trap intercepts the emergent carbanion. This stud...

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Detalles Bibliográficos
Autores principales: McLellan, Ross, Uzelac, Marina, Kennedy, Alan R., Hevia, Eva, Mulvey, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577511/
https://www.ncbi.nlm.nih.gov/pubmed/28662314
http://dx.doi.org/10.1002/anie.201706064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577511/
https://www.ncbi.nlm.nih.gov/pubmed/28662314
http://dx.doi.org/10.1002/anie.201706064

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