The Middle Fragment of Helicobacter pylori CagA Induces Actin Rearrangement and Triggers Its Own Uptake into Gastric Epithelial Cells

Cytotoxin-associated gene product A (CagA) is a major virulence factor secreted by Helicobacter pylori. CagA activity in the gastric epithelium is associated with higher risk of gastric cancer development. Bacterial type IV secretion system (T4SS)-mediated translocation of CagA into the cytosol of h...

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Detalles Bibliográficos
Autores principales: Tohidpour, Abolghasem, Gorrell, Rebecca J., Roujeinikova, Anna, Kwok, Terry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577571/
https://www.ncbi.nlm.nih.gov/pubmed/28788072
http://dx.doi.org/10.3390/toxins9080237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577571/
https://www.ncbi.nlm.nih.gov/pubmed/28788072
http://dx.doi.org/10.3390/toxins9080237

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