Insights into the Mechanisms Involved in Strong Hemorrhage and Dermonecrosis Induced by Atroxlysin-Ia, a PI-Class Snake Venom Metalloproteinase

Hemorrhage is the most prominent effect of snake venom metalloproteinases (SVMPs) in human envenomation. The capillary injury is a multifactorial effect caused by hydrolysis of the components of the basement membrane (BM). The PI and PIII classes of SVMPs are abundant in viperid venoms and hydrolyze...

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Detalles Bibliográficos
Autores principales: Freitas-de-Sousa, Luciana Aparecida, Colombini, Mônica, Lopes-Ferreira, Mônica, Serrano, Solange M. T., Moura-da-Silva, Ana Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577573/
https://www.ncbi.nlm.nih.gov/pubmed/28767072
http://dx.doi.org/10.3390/toxins9080239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577573/
https://www.ncbi.nlm.nih.gov/pubmed/28767072
http://dx.doi.org/10.3390/toxins9080239

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