Cargando…

Insights into the Mechanisms Involved in Strong Hemorrhage and Dermonecrosis Induced by Atroxlysin-Ia, a PI-Class Snake Venom Metalloproteinase

Hemorrhage is the most prominent effect of snake venom metalloproteinases (SVMPs) in human envenomation. The capillary injury is a multifactorial effect caused by hydrolysis of the components of the basement membrane (BM). The PI and PIII classes of SVMPs are abundant in viperid venoms and hydrolyze...

Descripción completa

Detalles Bibliográficos
Autores principales:	Freitas-de-Sousa, Luciana Aparecida, Colombini, Mônica, Lopes-Ferreira, Mônica, Serrano, Solange M. T., Moura-da-Silva, Ana Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577573/ https://www.ncbi.nlm.nih.gov/pubmed/28767072 http://dx.doi.org/10.3390/toxins9080239

Ejemplares similares

Engineered nanoparticles bind elapid snake venom toxins and inhibit venom-induced dermonecrosis
por: O’Brien, Jeffrey, et al.
Publicado: (2018)

Atroxlysin-III, A Metalloproteinase from the Venom of the Peruvian Pit Viper Snake Bothrops atrox (Jergón) Induces Glycoprotein VI Shedding and Impairs Platelet Function
por: Oliveira, Luciana S., et al.
Publicado: (2019)

Use of a Synthetic Biosensor for Neutralizing Activity-Biased Selection of Monoclonal Antibodies against Atroxlysin-I, an Hemorrhagic Metalloproteinase from Bothrops atrox Snake Venom
por: Schneider, Francisco Santos, et al.
Publicado: (2014)

Inflammatory Reaction Induced by Two Metalloproteinases Isolated from Bothrops atrox Venom and by Fragments Generated from the Hydrolysis of Basement Membrane Components
por: de Almeida, Michelle Teixeira, et al.
Publicado: (2020)

Functional Variability of Snake Venom Metalloproteinases: Adaptive Advantages in Targeting Different Prey and Implications for Human Envenomation
por: Bernardoni, Juliana L., et al.
Publicado: (2014)

Effects of copaiba oil on dermonecrosis induced by Loxosceles intermedia venom
por: Ribeiro, Mara Fernandes, et al.
Publicado: (2019)

Systemic Effects of Hemorrhagic Snake Venom Metalloproteinases: Untargeted Peptidomics to Explore the Pathodegradome of Plasma Proteins
por: Bertholim, Luciana, et al.
Publicado: (2021)

Diversity of metalloproteinases in Bothrops neuwiedi snake venom transcripts: evidences for recombination between different classes of SVMPs
por: Moura-da-Silva, Ana M, et al.
Publicado: (2011)

Cleavage of proteoglycans, plasma proteins and the platelet-derived growth factor receptor in the hemorrhagic process induced by snake venom metalloproteinases
por: Asega, Amanda F., et al.
Publicado: (2020)

Processing of Snake Venom Metalloproteinases: Generation of Toxin Diversity and Enzyme Inactivation
por: Moura-da-Silva, Ana M., et al.
Publicado: (2016)

Inhibition of a Snake Venom Metalloproteinase by the Flavonoid Myricetin
por: Preciado, Lina María, et al.
Publicado: (2018)

Snake Venom Metalloproteinases and Their Peptide Inhibitors from Myanmar Russell’s Viper Venom
por: Yee, Khin Than, et al.
Publicado: (2016)

Mechanisms of Vascular Damage by Hemorrhagic Snake Venom Metalloproteinases: Tissue Distribution and In Situ Hydrolysis
por: Baldo, Cristiani, et al.
Publicado: (2010)

Temporal evolution of dermonecrosis in loxoscelism assessed by photodocumentation
por: Borrasca-Fernandes, Carla Fernanda, et al.
Publicado: (2022)

Snake Venom Metalloproteinases (SVMPs): A structure-function update
por: Olaoba, Olamide Tosin, et al.
Publicado: (2020)

Sphingomyelinase D from Loxosceles laeta Venom Induces the Expression of MMP7 in Human Keratinocytes: Contribution to Dermonecrosis
por: Corrêa, Mara A., et al.
Publicado: (2016)

Structures and Functions of Snake Venom Metalloproteinases (SVMP) from Protobothrops venom Collected in Japan
por: Oyama, Etsuko, et al.
Publicado: (2017)

P-I Snake Venom Metalloproteinase Is Able to Activate the Complement System by Direct Cleavage of Central Components of the Cascade
por: Pidde-Queiroz, Giselle, et al.
Publicado: (2013)

Hemorrhage Caused by Snake Venom Metalloproteinases: A Journey of Discovery and Understanding †
por: Gutiérrez, José María, et al.
Publicado: (2016)

Independent Recruitment of Different Types of Phospholipases A2 to the Venoms of Caenophidian Snakes: The Rise of PLA(2)-IIE within Pseudoboini (Dipsadidae)
por: Bayona-Serrano, Juan David, et al.
Publicado: (2023)

The Venom Composition of the Snake Tribe Philodryadini: ‘Omic’ Techniques Reveal Intergeneric Variability among South American Racers
por: Tioyama, Emilly Campos, et al.
Publicado: (2023)

ADAM and ADAMTS Family Proteins and Snake Venom Metalloproteinases: A Structural Overview
por: Takeda, Soichi
Publicado: (2016)

Understanding the Snake Venom Metalloproteinases: An Interview with Jay Fox and José María Gutiérrez
por: Fox, Jay W., et al.
Publicado: (2017)

Snakes, Snake Venoms, and Antivenenes
por: Ranck, E. M.
Publicado: (1902)

Naja annulifera Snake: New insights into the venom components and pathogenesis of envenomation
por: Silva-de-França, Felipe, et al.
Publicado: (2019)

Acute kidney injury and dermonecrosis after Loxosceles reclusa envenomation
por: Nag, A., et al.
Publicado: (2014)

Evidence for Snake Venom Plasticity in a Long-Term Study with Individual Captive Bothrops atrox
por: Amazonas, Diana R., et al.
Publicado: (2019)

Complement System Inhibition Modulates the Pro-Inflammatory Effects of a Snake Venom Metalloproteinase
por: Luchini, Lygia Samartin Gonçalves, et al.
Publicado: (2019)

Computational B-cell epitope identification and production of neutralizing murine antibodies against Atroxlysin-I
por: Kozlova, Edgar Ernesto Gonzalez, et al.
Publicado: (2018)

Involvement of von Willebrand factor and botrocetin in the thrombocytopenia induced by Bothrops jararaca snake venom
por: Thomazini, Camila Martos, et al.
Publicado: (2021)

Researches on Snake-Venom
por: Mitchell, S. Weir
Publicado: (1885)

Snake Venoms in Medicine
por: Chopra, R. N., et al.
Publicado: (1932)

Snake Venom in Therapeutics
Publicado: (1937)

Pharmacokinetics of Snake Venom
por: Sanhajariya, Suchaya, et al.
Publicado: (2018)

Tissue Localization and Extracellular Matrix Degradation by PI, PII and PIII Snake Venom Metalloproteinases: Clues on the Mechanisms of Venom-Induced Hemorrhage
por: Herrera, Cristina, et al.
Publicado: (2015)

Bmoo FIBMP-I: A New Fibrinogenolytic Metalloproteinase from Bothrops moojeni Snake Venom
por: Torres, F. S., et al.
Publicado: (2012)

Direct Fibrinolytic Snake Venom Metalloproteinases Affecting Hemostasis: Structural, Biochemical Features and Therapeutic Potential
por: Sanchez, Eladio F., et al.
Publicado: (2017)

Corrigendum: Complement System Inhibition Modulates the Pro-Inflammatory Effects of a Snake Venom Metalloproteinase
por: Luchini, Lygia Samartin Gonçalves, et al.
Publicado: (2019)

Potential of Matrix Metalloproteinase Inhibitors for the Treatment of Local Tissue Damage Induced by a Type P-I Snake Venom Metalloproteinase
por: Preciado, Lina María, et al.
Publicado: (2019)

Diversity of Phospholipases A(2) from Bothrops atrox Snake Venom: Adaptive Advantages for Snakes Compromising Treatments for Snakebite Patients
por: Sousa, Leijiane F., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_oj554adcu381k50fe8l01muqmf