Sex Is a Determinant for Deoxynivalenol Metabolism and Elimination in the Mouse

Based on prior observations that deoxynivalenol (DON) toxicity is sex-dependent, we compared metabolism and clearance of this toxin in male and female mice. Following intraperitoneal challenge with 1 mg/kg bw DON, the dose used in the aforementioned toxicity study, ELISA and LC–MS/MS analyses reveal...

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Detalles Bibliográficos
Autores principales: Pestka, James J., Clark, Erica S., Schwartz-Zimmermann, Heidi E., Berthiller, Franz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577574/
https://www.ncbi.nlm.nih.gov/pubmed/28777306
http://dx.doi.org/10.3390/toxins9080240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577574/
https://www.ncbi.nlm.nih.gov/pubmed/28777306
http://dx.doi.org/10.3390/toxins9080240

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