Sinulariolide Suppresses Cell Migration and Invasion by Inhibiting Matrix Metalloproteinase-2/-9 and Urokinase through the PI3K/AKT/mTOR Signaling Pathway in Human Bladder Cancer Cells

Sinulariolide is a natural product extracted from the cultured-type soft coral Sinularia flexibilis, and possesses bioactivity against the movement of several types of cancer cells. However, the molecular pathway behind its effects on human bladder cancer remain poorly understood. Using a human blad...

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Detalles Bibliográficos
Autores principales: Cheng, Te-Chih, Din, Zhong-Hao, Su, Jui-Hsin, Wu, Yu-Jen, Liu, Chih-I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577593/
https://www.ncbi.nlm.nih.gov/pubmed/28767067
http://dx.doi.org/10.3390/md15080238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577593/
https://www.ncbi.nlm.nih.gov/pubmed/28767067
http://dx.doi.org/10.3390/md15080238

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