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Sinulariolide Suppresses Cell Migration and Invasion by Inhibiting Matrix Metalloproteinase-2/-9 and Urokinase through the PI3K/AKT/mTOR Signaling Pathway in Human Bladder Cancer Cells
Sinulariolide is a natural product extracted from the cultured-type soft coral Sinularia flexibilis, and possesses bioactivity against the movement of several types of cancer cells. However, the molecular pathway behind its effects on human bladder cancer remain poorly understood. Using a human blad...
Autores principales: | Cheng, Te-Chih, Din, Zhong-Hao, Su, Jui-Hsin, Wu, Yu-Jen, Liu, Chih-I |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577593/ https://www.ncbi.nlm.nih.gov/pubmed/28767067 http://dx.doi.org/10.3390/md15080238 |
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