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The Neuroprotective Marine Compound Psammaplysene A Binds the RNA-Binding Protein HNRNPK

In previous work, we characterized the strong neuroprotective properties of the marine compound Psammaplysene A (PA) in in vitro and in vivo models of neurodegeneration. Based on its strong neuroprotective activity, the current work attempts to identify the physical target of PA to gain mechanistic...

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Detalles Bibliográficos
Autores principales: Boccitto, Marco, Lee, Nayoung, Sakamoto, Satoshi, Spruce, Lynn A., Handa, Hiroshi, Clardy, Jon, Seeholzer, Steven H., Kalb, Robert G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577601/
https://www.ncbi.nlm.nih.gov/pubmed/28783126
http://dx.doi.org/10.3390/md15080246