A Novel High-Mannose Specific Lectin from the Green Alga Halimeda renschii Exhibits a Potent Anti-Influenza Virus Activity through High-Affinity Binding to the Viral Hemagglutinin

We have isolated a novel lectin, named HRL40 from the green alga Halimeda renschii. In hemagglutination-inhibition test and oligosaccharide-binding experiment with 29 pyridylaminated oligosaccharides, HRL40 exhibited a strict binding specificity for high-mannose N-glycans having an exposed (α1-3) ma...

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Detalles Bibliográficos
Autores principales: Mu, Jinmin, Hirayama, Makoto, Sato, Yuichiro, Morimoto, Kinjiro, Hori, Kanji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577609/
https://www.ncbi.nlm.nih.gov/pubmed/28813016
http://dx.doi.org/10.3390/md15080255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577609/
https://www.ncbi.nlm.nih.gov/pubmed/28813016
http://dx.doi.org/10.3390/md15080255

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