Genetic Validation of Leishmania donovani Lysyl-tRNA Synthetase Shows that It Is Indispensable for Parasite Growth and Infectivity

Leishmania donovani is a protozoan parasite that causes visceral leishmaniasis. Increasing resistance and severe side effects of existing drugs have led to the need to identify new chemotherapeutic targets. Aminoacyl-tRNA synthetases (aaRSs) are ubiquitous and are required for protein synthesis. aaR...

Descripción completa

Detalles Bibliográficos
Autores principales: Chadha, Sanya, Mallampudi, N. Arjunreddy, Mohapatra, Debendra K., Madhubala, Rentala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577655/
https://www.ncbi.nlm.nih.gov/pubmed/28875178
http://dx.doi.org/10.1128/mSphereDirect.00340-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577655/
https://www.ncbi.nlm.nih.gov/pubmed/28875178
http://dx.doi.org/10.1128/mSphereDirect.00340-17

Ejemplares similares