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Genetic Validation of Leishmania donovani Lysyl-tRNA Synthetase Shows that It Is Indispensable for Parasite Growth and Infectivity

Leishmania donovani is a protozoan parasite that causes visceral leishmaniasis. Increasing resistance and severe side effects of existing drugs have led to the need to identify new chemotherapeutic targets. Aminoacyl-tRNA synthetases (aaRSs) are ubiquitous and are required for protein synthesis. aaR...

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Detalles Bibliográficos
Autores principales:	Chadha, Sanya, Mallampudi, N. Arjunreddy, Mohapatra, Debendra K., Madhubala, Rentala
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577655/ https://www.ncbi.nlm.nih.gov/pubmed/28875178 http://dx.doi.org/10.1128/mSphereDirect.00340-17

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