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Spatial and temporal epithelial ovarian cancer cell heterogeneity impacts Maraba virus oncolytic potential
BACKGROUND: Epithelial ovarian cancer exhibits extensive interpatient and intratumoral heterogeneity, which can hinder successful treatment strategies. Herein, we investigated the efficacy of an emerging oncolytic, Maraba virus (MRBV), in an in vitro model of ovarian tumour heterogeneity. METHODS: F...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577660/ https://www.ncbi.nlm.nih.gov/pubmed/28854921 http://dx.doi.org/10.1186/s12885-017-3600-2 |