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Spatial and temporal epithelial ovarian cancer cell heterogeneity impacts Maraba virus oncolytic potential

BACKGROUND: Epithelial ovarian cancer exhibits extensive interpatient and intratumoral heterogeneity, which can hinder successful treatment strategies. Herein, we investigated the efficacy of an emerging oncolytic, Maraba virus (MRBV), in an in vitro model of ovarian tumour heterogeneity. METHODS: F...

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Detalles Bibliográficos
Autores principales:	Tong, Jessica G., Valdes, Yudith Ramos, Sivapragasam, Milani, Barrett, John W., Bell, John C., Stojdl, David, DiMattia, Gabriel E., Shepherd, Trevor G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577660/ https://www.ncbi.nlm.nih.gov/pubmed/28854921 http://dx.doi.org/10.1186/s12885-017-3600-2

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