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Comparison between next-generation and Sanger-based sequencing for the detection of transmitted drug-resistance mutations among recently infected HIV-1 patients in Israel, 2000–2014

Introduction: Transmitted drug-resistance mutations (TDRM) may hamper successful anti-HIV-1 therapy and impact future control of the HIV-1 epidemic. Recently infected, therapy-naïve individuals are best suited for surveillance of such TDRM. In this study, TDRM, detected by next-generation sequencing...

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Detalles Bibliográficos
Autores principales: Moscona, Roy, Ram, Daniela, Wax, Marina, Bucris, Efrat, Levy, Itzchak, Mendelson, Ella, Mor, Orna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577736/
https://www.ncbi.nlm.nih.gov/pubmed/28799325
http://dx.doi.org/10.7448/IAS.20.1.21846