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Rosiglitazone increases endothelial cell migration and vascular permeability through Akt phosphorylation

BACKGROUND: Thiazolidinediones (TZDs), peroxisome proliferator-activated receptor-γ (PPAR-γ) agonists, exhibit anti-inflammatory and antioxidant properties and inhibit endothelial inflammation and dysfunction, which is anti-atherogenic. However, fluid retention, which may lead to congestive heart fa...

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Detalles Bibliográficos
Autores principales: Ku, Yun Hyi, Cho, Bong-Jun, Kim, Min Joo, Lim, Soo, Park, Young Joo, Jang, Hak C., Choi, Sung Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577739/
https://www.ncbi.nlm.nih.gov/pubmed/28854981
http://dx.doi.org/10.1186/s40360-017-0169-y