Identification of two mutation sites in spike and envelope proteins mediating optimal cellular infection of porcine epidemic diarrhea virus from different pathways

Entry of the α-coronavirus porcine epidemic diarrhea virus (PEDV) requires specific proteases to activate spike (S) protein for the membrane fusion of the virion to the host cell following receptor binding. Herein, PEDV isolate 85-7 could proliferate and induce cell–cell fusion in a trypsin independ...

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Detalles Bibliográficos
Autores principales: Sun, Min, Ma, Jiale, Yu, Zeyanqiu, Pan, Zihao, Lu, Chengping, Yao, Huochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577753/
https://www.ncbi.nlm.nih.gov/pubmed/28854955
http://dx.doi.org/10.1186/s13567-017-0449-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577753/
https://www.ncbi.nlm.nih.gov/pubmed/28854955
http://dx.doi.org/10.1186/s13567-017-0449-y

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