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Optimized reduced representation bisulfite sequencing reveals tissue-specific mCHH islands in maize
BACKGROUND: DNA methylation plays important roles in many regulatory processes in plants. It is economically infeasible to profile genome-wide DNA methylation at a single-base resolution in maize, given its genome size of ~2.5 Gb. As an alternative, we adapted region of interest (ROI)-directed reduc...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577757/ https://www.ncbi.nlm.nih.gov/pubmed/28854962 http://dx.doi.org/10.1186/s13072-017-0148-y |