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Up-regulation of lncRNA CASC9 promotes esophageal squamous cell carcinoma growth by negatively regulating PDCD4 expression through EZH2

BACKGROUND: Abnormal expression of numerous long non-coding RNAs (lncRNAs) has been reported in esophageal squamous cell carcinoma (ESCC) recently, but the great majority of their roles and mechanisms remain largely unclear. We aim to identify the critical ESCC-associated lncRNAs and elucidate the f...

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Detalles Bibliográficos
Autores principales: Wu, Yuanyuan, Hu, Liwen, Liang, Yan, Li, Juan, Wang, Kai, Chen, Xuedan, Meng, Hui, Guan, Xingying, Yang, Kang, Bai, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577767/
https://www.ncbi.nlm.nih.gov/pubmed/28854977
http://dx.doi.org/10.1186/s12943-017-0715-7