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Safety and in vivo immune assessment of escalating doses of oral laquinimod in patients with RRMS

BACKGROUND: Laquinimod is an oral immunomodulator in clinical development to treat relapsing-remitting multiple sclerosis (RRMS). Laquinimod is in clinical development for the treatment of multiple sclerosis and Huntington Disease (HD). The objective of this study is to assess the safety, tolerabili...

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Detalles Bibliográficos
Autores principales: Ziemssen, Tjalf, Tumani, Hayrettin, Sehr, Tony, Thomas, Katja, Paul, Friedemann, Richter, Nils, Samara, Emil, Spiegelstein, Ofer, Sorani, Ella, Bar-Ilan, Oren, Mimrod, Dorit, Hayardeny, Liat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577769/
https://www.ncbi.nlm.nih.gov/pubmed/28859672
http://dx.doi.org/10.1186/s12974-017-0945-z