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Clinical implications of neoepitope landscapes for adult and pediatric cancers

Many immunotherapies rely on the presence of neoepitopes derived from somatic mutations that lead to altered peptide sequences. Several studies have now analyzed the neoepitope landscape of different cancer subtypes, predominantly for adult samples, which tend to feature significantly higher mutatio...

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Detalles Bibliográficos
Autores principales: Feng, Yang-Yang, Griffith, Obi L., Griffith, Malachi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577778/
https://www.ncbi.nlm.nih.gov/pubmed/28854952
http://dx.doi.org/10.1186/s13073-017-0470-9