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Effects and mechanism of dexmedetomidine on neuronal cell injury induced by hypoxia-ischemia

BACKGROUND: The present study aims to investigate the protective effects of dexmedetomidine (DMED) on hypoxia ischemia injury induced by oxygen and glucose deprivation (OGD) in PC12 and primary neuronal cells. METHODS: PC12 cells exposed to OGD was used to establish ischemia model. The OGD-induced c...

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Detalles Bibliográficos
Autores principales: Liu, Ya-Jun, Wang, Duan-Yu, Yang, Yong-Jian, Lei, Wei-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577810/
https://www.ncbi.nlm.nih.gov/pubmed/28854873
http://dx.doi.org/10.1186/s12871-017-0413-4