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Ultra-low dose of rituximab in rheumatoid arthritis: study protocol for a randomised controlled trial

BACKGROUND: A standard low-dosing schedule of rituximab (RTX; 2 × 500 mg or 1 × 1000 mg) is as effective for active rheumatoid arthritis (RA) as the registered dose (2 × 1000 mg). Moreover, several small uncontrolled studies suggest that even lower-dosed treatment with RTX also leads to good treatme...

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Detalles Bibliográficos
Autores principales: den Broeder, Alfons A., Verhoef, Lise M., Fransen, Jaap, Thurlings, Rogier, van den Bemt, Bart J. F., Teerenstra, Steven, Boers, Nadine, den Broeder, Nathan, van den Hoogen, Frank H. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577818/
https://www.ncbi.nlm.nih.gov/pubmed/28854956
http://dx.doi.org/10.1186/s13063-017-2134-x