Gefitinib-loaded DSPE-PEG2000 nanomicelles with CD133 aptamers target lung cancer stem cells

BACKGROUND: Lung cancer stem cells (CSCs) are considered to be the seed of lung cancer, and CD133 is a marker of lung CSCs. Here, we developed gefitinib-loaded poly(ethylene glycol) 2000-distearoylphosphatidylethanolamine nanomicelles with CD133 aptamers (M-Gef-CD133) to eliminate CD133(+) lung CSCs...

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Detalles Bibliográficos
Autores principales: Huang, Xiaolong, Huang, Jingsong, Leng, Dewen, Yang, Shuo, Yao, Qi, Sun, Jin, Hu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577827/
https://www.ncbi.nlm.nih.gov/pubmed/28854941
http://dx.doi.org/10.1186/s12957-017-1230-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577827/
https://www.ncbi.nlm.nih.gov/pubmed/28854941
http://dx.doi.org/10.1186/s12957-017-1230-4

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