Genome-wide DNA methylation analysis in blood cells from patients with Werner syndrome

BACKGROUND: Werner syndrome is a progeroid disorder characterized by premature age-related phenotypes. Although it is well established that autosomal recessive mutations in the WRN gene is responsible for Werner syndrome, the molecular alterations that lead to disease phenotype remain still unidenti...

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Detalles Bibliográficos
Autores principales: Guastafierro, T., Bacalini, M. G., Marcoccia, A., Gentilini, D., Pisoni, S., Di Blasio, A. M., Corsi, A., Franceschi, C., Raimondo, D., Spanò, A., Garagnani, P., Bondanini, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577832/
https://www.ncbi.nlm.nih.gov/pubmed/28861129
http://dx.doi.org/10.1186/s13148-017-0389-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577832/
https://www.ncbi.nlm.nih.gov/pubmed/28861129
http://dx.doi.org/10.1186/s13148-017-0389-4

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