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N1-Src Kinase Is Required for Primary Neurogenesis in Xenopus tropicalis

The presence of the neuronal-specific N1-Src splice variant of the C-Src tyrosine kinase is conserved through vertebrate evolution, suggesting an important role in complex nervous systems. Alternative splicing involving an N1-Src-specific microexon leads to a 5 or 6 aa insertion into the SH3 domain...

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Detalles Bibliográficos
Autores principales: Lewis, Philip A., Bradley, Isobel C., Pizzey, Alastair R., Isaacs, Harry V., Evans, Gareth J.O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577857/
https://www.ncbi.nlm.nih.gov/pubmed/28765332
http://dx.doi.org/10.1523/JNEUROSCI.3881-16.2017