Inhibition of proteolytic cleavage of the hemagglutinin of influenza virus by the calcium-specific ionophore A23187.

At calcium-specific ionophore A23187 concentrations of approximately 0.25 microM [which still allow assembly and release of fowl plague virus (FPV) particles] post-translational proteolytic cleavage of the viral hemagglutinin precursor HA into the fragments HA1 and HA2 is inhibited. The resulting vi...

Descripción completa

Detalles Bibliográficos
Autores principales: Klenk, H D, Garten, W, Rott, R
Formato: Texto
Lenguaje:English
Publicado: 1984
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC557788/
https://www.ncbi.nlm.nih.gov/pubmed/6441705

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC557788/
https://www.ncbi.nlm.nih.gov/pubmed/6441705

Ejemplares similares