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Inhibition of proteolytic cleavage of the hemagglutinin of influenza virus by the calcium-specific ionophore A23187.
At calcium-specific ionophore A23187 concentrations of approximately 0.25 microM [which still allow assembly and release of fowl plague virus (FPV) particles] post-translational proteolytic cleavage of the viral hemagglutinin precursor HA into the fragments HA1 and HA2 is inhibited. The resulting vi...
Autores principales: | Klenk, H D, Garten, W, Rott, R |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
1984
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC557788/ https://www.ncbi.nlm.nih.gov/pubmed/6441705 |
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