Cargando…

Assembly rules for GABA(A) receptor complexes in the brain

GABA(A) receptor (GABA(A)R) pentamers are assembled from a pool of 19 subunits, and variety in subunit combinations diversifies GABA(A)R functions to tune brain activity. Pentamers with distinct subunit compositions localize differentially at synaptic and non-synaptic sites to mediate phasic and ton...

Descripción completa

Detalles Bibliográficos
Autores principales: Martenson, James S, Yamasaki, Tokiwa, Chaudhury, Nashid H, Albrecht, David, Tomita, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577914/
https://www.ncbi.nlm.nih.gov/pubmed/28816653
http://dx.doi.org/10.7554/eLife.27443