Loss of the melanocortin-4 receptor in mice causes dilated cardiomyopathy

Haploinsufficiency of the melanocortin-4 receptor, the most common monogenetic obesity syndrome in humans, is associated with a reduction in autonomic tone, bradycardia, and incidence of obesity-associated hypertension. Thus, it has been assumed that melanocortin obesity syndrome may be protective w...

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Detalles Bibliográficos
Autores principales: Litt, Michael J, Okoye, G Donald, Lark, Daniel, Cakir, Isin, Moore, Christy, Barber, Mary C, Atkinson, James, Fessel, Josh, Moslehi, Javid, Cone, Roger D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Human Biology and Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577919/
https://www.ncbi.nlm.nih.gov/pubmed/28829041
http://dx.doi.org/10.7554/eLife.28118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577919/
https://www.ncbi.nlm.nih.gov/pubmed/28829041
http://dx.doi.org/10.7554/eLife.28118

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