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Clinical Outcomes and Co-Occurring Mutations in Patients with RUNX1-Mutated Acute Myeloid Leukemia

(1) Runt-related transcription factor 1 (RUNX1) mutations in acute myeloid leukemia (AML) are often associated with worse prognosis. We assessed co-occurring mutations, response to therapy, and clinical outcomes in patients with and without mutant RUNX1 (mRUNX1); (2) We analyzed 328 AML patients, in...

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Detalles Bibliográficos
Autores principales: Khan, Maliha, Cortes, Jorge, Kadia, Tapan, Naqvi, Kiran, Brandt, Mark, Pierce, Sherry, Patel, Keyur P., Borthakur, Gautam, Ravandi, Farhad, Konopleva, Marina, Kornblau, Steven, Kantarjian, Hagop, Bhalla, Kapil, DiNardo, Courtney D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578010/
https://www.ncbi.nlm.nih.gov/pubmed/28933735
http://dx.doi.org/10.3390/ijms18081618