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Clinical Role of ASCT2 (SLC1A5) in KRAS-Mutated Colorectal Cancer

Mutation in the KRAS gene induces prominent metabolic changes. We have recently reported that KRAS mutations in colorectal cancer (CRC) cause alterations in amino acid metabolism. However, it remains to be investigated which amino acid transporter can be regulated by mutated KRAS in CRC. Here, we pe...

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Detalles Bibliográficos
Autores principales: Toda, Kosuke, Nishikawa, Gen, Iwamoto, Masayoshi, Itatani, Yoshiro, Takahashi, Ryo, Sakai, Yoshiharu, Kawada, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578022/
https://www.ncbi.nlm.nih.gov/pubmed/28749408
http://dx.doi.org/10.3390/ijms18081632