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Tumor-Stroma Crosstalk in Bone Tissue: The Osteoclastogenic Potential of a Breast Cancer Cell Line in a Co-Culture System and the Role of EGFR Inhibition

Although bone metastases represent a major challenge in the natural history of breast cancer (BC), the complex interactions involved have hindered the development of robust in vitro models. The aim of this work is the development of a preclinical model of cancer and bone stromal cells to mimic the b...

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Detalles Bibliográficos
Autores principales: Mercatali, Laura, La Manna, Federico, Miserocchi, Giacomo, Liverani, Chiara, De Vita, Alessandro, Spadazzi, Chiara, Bongiovanni, Alberto, Recine, Federica, Amadori, Dino, Ghetti, Martina, Ibrahim, Toni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578045/
https://www.ncbi.nlm.nih.gov/pubmed/28758931
http://dx.doi.org/10.3390/ijms18081655